甲基苯丙胺治好了我的可卡因瘾。

Colin N Haile, Richard De La Garza, Thomas F Newton
{"title":"甲基苯丙胺治好了我的可卡因瘾。","authors":"Colin N Haile,&nbsp;Richard De La Garza,&nbsp;Thomas F Newton","doi":"10.4172/2155-6105.1000103","DOIUrl":null,"url":null,"abstract":"<p><p>Cocaine dependence is an enduring problem and years of research and drug development has yet to produce an efficacious pharmacotherapy. Recent clinical research suggests that chronic treatment with amphetamine-like medications produces tolerance to cocaine's reinforcing effects and may offer a viable pharmacotherapy. Three methamphetamine-dependent participants that had been in our clinical laboratory experiments and previously addicted to cocaine are reviewed. Data obtained from initial screen and informal conversation suggested that all participants considered methamphetamine to have helped them stop using cocaine and eliminate cocaine craving. Methamphetamine also significantly decreased their alcohol consumption but did not alter cannabis or nicotine use.</p>","PeriodicalId":73583,"journal":{"name":"Journal of addiction research & therapy","volume":"1 103","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2010-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2155-6105.1000103","citationCount":"5","resultStr":"{\"title\":\"Methamphetamine Cured my Cocaine Addiction.\",\"authors\":\"Colin N Haile,&nbsp;Richard De La Garza,&nbsp;Thomas F Newton\",\"doi\":\"10.4172/2155-6105.1000103\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Cocaine dependence is an enduring problem and years of research and drug development has yet to produce an efficacious pharmacotherapy. Recent clinical research suggests that chronic treatment with amphetamine-like medications produces tolerance to cocaine's reinforcing effects and may offer a viable pharmacotherapy. Three methamphetamine-dependent participants that had been in our clinical laboratory experiments and previously addicted to cocaine are reviewed. Data obtained from initial screen and informal conversation suggested that all participants considered methamphetamine to have helped them stop using cocaine and eliminate cocaine craving. Methamphetamine also significantly decreased their alcohol consumption but did not alter cannabis or nicotine use.</p>\",\"PeriodicalId\":73583,\"journal\":{\"name\":\"Journal of addiction research & therapy\",\"volume\":\"1 103\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-10-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.4172/2155-6105.1000103\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of addiction research & therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2155-6105.1000103\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of addiction research & therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2155-6105.1000103","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5

摘要

可卡因依赖是一个持久的问题,多年的研究和药物开发尚未产生有效的药物治疗。最近的临床研究表明,长期使用类似安非他明的药物治疗可以产生对可卡因强化作用的耐受性,这可能是一种可行的药物治疗方法。三名甲基苯丙胺依赖的参与者曾在我们的临床实验室实验和以前上瘾的可卡因进行审查。从初步筛选和非正式谈话中获得的数据表明,所有参与者都认为甲基苯丙胺帮助他们停止使用可卡因并消除对可卡因的渴望。甲基苯丙胺也显著减少了他们的酒精消费量,但没有改变大麻或尼古丁的使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Methamphetamine Cured my Cocaine Addiction.

Cocaine dependence is an enduring problem and years of research and drug development has yet to produce an efficacious pharmacotherapy. Recent clinical research suggests that chronic treatment with amphetamine-like medications produces tolerance to cocaine's reinforcing effects and may offer a viable pharmacotherapy. Three methamphetamine-dependent participants that had been in our clinical laboratory experiments and previously addicted to cocaine are reviewed. Data obtained from initial screen and informal conversation suggested that all participants considered methamphetamine to have helped them stop using cocaine and eliminate cocaine craving. Methamphetamine also significantly decreased their alcohol consumption but did not alter cannabis or nicotine use.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信