单倍体进化构造:新特征和进一步挑战。

Q2 Medicine

In Silico Biology Pub Date : 2011-01-01 DOI:10.3233/ISB-2012-0447

Sergey A Lashin, Yury G Matushkin

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引用次数: 9

摘要

在本文中，我们考虑了在模拟原核生物群落进化的方法学的最新进展和新功能的软件包“Haploid evolutionary constructor”(http://evol-constructor.bionet.nsc.ru)。我们展示了在我们的软件工具中构建复杂计算机模型的原理。这些模型描述了几个层次的生物组织:遗传、代谢、种群、生态。单倍体进化构造器的新特征包括基因网络和噬菌体感染的建模。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Haploid evolutionary constructor: new features and further challenges.

In this paper we consider the recent advances in methodology for modeling of prokaryotic communities evolution and new features of the software package "Haploid evolutionary constructor" (http://evol-constructor.bionet.nsc.ru). We show the principles of building complex computer models in our software tool. These models describe several levels of biological organization: genetic, metabolic, population, ecological. New features of the haploid evolutionary constructor include the modeling of gene networks and phage infections.

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来源期刊

In Silico Biology Computer Science-Computational Theory and Mathematics

CiteScore

2.20

自引率

0.00%

发文量

期刊介绍： The considerable "algorithmic complexity" of biological systems requires a huge amount of detailed information for their complete description. Although far from being complete, the overwhelming quantity of small pieces of information gathered for all kind of biological systems at the molecular and cellular level requires computational tools to be adequately stored and interpreted. Interpretation of data means to abstract them as much as allowed to provide a systematic, an integrative view of biology. Most of the presently available scientific journals focus either on accumulating more data from elaborate experimental approaches, or on presenting new algorithms for the interpretation of these data. Both approaches are meritorious.