多发性骨髓瘤的治愈率。

Bone Marrow Research Pub Date : 2012-01-01 Epub Date: 2012-05-23 DOI:10.1155/2012/916479
Raymond Alexanian, Kay Delasalle, Michael Wang, Sheeba Thomas, Donna Weber
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引用次数: 25

摘要

在1987年至2010年接受治疗并在18个月后评估的792例多发性骨髓瘤患者中,167例患者完全缓解。在1987-1998年治疗的60例患者中,随访时间较长,最近一次复发发生在11.8年后,因此有13例患者持续完全缓解超过12年(范围12-22年)。这些结果表明,在此期间接受治疗的所有患者中有3%可能治愈多发性骨髓瘤。除了免疫固定外,更敏感的残留疾病检测技术应该更一致地应用于明显完全缓解的患者,以识别那些有治愈潜力的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Curability of multiple myeloma.

Curability of multiple myeloma.

Curability of multiple myeloma.

Among 792 patients with multiple myeloma treated from 1987 to 2010 and assessed after 18 months, there were 167 patients with complete remission. For those 60 patients treated between 1987-1998 and with long followup, the latest relapse occurred after 11.8 years, so that 13 patients have remained in sustained complete remission for longer than 12 years (range 12-22 years). These results suggest that 3% of all patients treated during that period may be cured of multiple myeloma. In addition to immunofixation, more sensitive techniques for the detection of residual disease should be applied more consistently in patients with apparent complete remission in order to identify those with potential cure.

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