{"title":"鼻咽部非角化(未分化)畸形细胞癌。一份病例报告。","authors":"Arzu Avci, Omer Günhan, Yildirim Karslioğlu, Bulent Celasun","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The histologic type of nasopharyngeal carcinoma can be an important factor in the prognosis. The effects, if any, of the degree of cellular pleomorphism is uncertain.</p><p><strong>Case: </strong>In this report, we present a case of nonkeratinizing, undifferentiated nasopharyngeal carcinoma with monstrous tumor giant cells. An extremely high level of aneuploidy and dense cytoplasmic accumulation of Epstein-Barr virus capsid antigen were found in tumor cells. The patient was treated with concomitant chemoradiotherapy.</p><p><strong>Conclusion: </strong>Nine years of follow-up with no recurrences suggests that this extreme morphologic variation may impart no adverse prognostic effect.</p>","PeriodicalId":76995,"journal":{"name":"Analytical and quantitative cytology and histology","volume":"33 5","pages":"297-302"},"PeriodicalIF":0.0000,"publicationDate":"2011-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nasopharyngeal nonkeratinizing (undifferentiated) monstrous cell carcinoma. A case report.\",\"authors\":\"Arzu Avci, Omer Günhan, Yildirim Karslioğlu, Bulent Celasun\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The histologic type of nasopharyngeal carcinoma can be an important factor in the prognosis. The effects, if any, of the degree of cellular pleomorphism is uncertain.</p><p><strong>Case: </strong>In this report, we present a case of nonkeratinizing, undifferentiated nasopharyngeal carcinoma with monstrous tumor giant cells. An extremely high level of aneuploidy and dense cytoplasmic accumulation of Epstein-Barr virus capsid antigen were found in tumor cells. The patient was treated with concomitant chemoradiotherapy.</p><p><strong>Conclusion: </strong>Nine years of follow-up with no recurrences suggests that this extreme morphologic variation may impart no adverse prognostic effect.</p>\",\"PeriodicalId\":76995,\"journal\":{\"name\":\"Analytical and quantitative cytology and histology\",\"volume\":\"33 5\",\"pages\":\"297-302\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analytical and quantitative cytology and histology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical and quantitative cytology and histology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nasopharyngeal nonkeratinizing (undifferentiated) monstrous cell carcinoma. A case report.
Background: The histologic type of nasopharyngeal carcinoma can be an important factor in the prognosis. The effects, if any, of the degree of cellular pleomorphism is uncertain.
Case: In this report, we present a case of nonkeratinizing, undifferentiated nasopharyngeal carcinoma with monstrous tumor giant cells. An extremely high level of aneuploidy and dense cytoplasmic accumulation of Epstein-Barr virus capsid antigen were found in tumor cells. The patient was treated with concomitant chemoradiotherapy.
Conclusion: Nine years of follow-up with no recurrences suggests that this extreme morphologic variation may impart no adverse prognostic effect.
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