{"title":"RNA-DNA序列的差异导致了遗传密码的模糊性。","authors":"Thomas Bentin, Michael L Nielsen","doi":"10.4161/adna.17086","DOIUrl":null,"url":null,"abstract":"<p><p>A recent paper in Science by Li et al. 2011(1) reports widespread sequence differences in the human transcriptome between RNAs and their encoding genes termed RNA-DNA differences (RDDs). The findings could add a new layer of complexity to gene expression but the study has been criticized. </p>","PeriodicalId":8444,"journal":{"name":"Artificial DNA: PNA & XNA","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4161/adna.17086","citationCount":"1","resultStr":"{\"title\":\"RNA-DNA sequence differences spell genetic code ambiguities.\",\"authors\":\"Thomas Bentin, Michael L Nielsen\",\"doi\":\"10.4161/adna.17086\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A recent paper in Science by Li et al. 2011(1) reports widespread sequence differences in the human transcriptome between RNAs and their encoding genes termed RNA-DNA differences (RDDs). The findings could add a new layer of complexity to gene expression but the study has been criticized. </p>\",\"PeriodicalId\":8444,\"journal\":{\"name\":\"Artificial DNA: PNA & XNA\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.4161/adna.17086\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Artificial DNA: PNA & XNA\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4161/adna.17086\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Artificial DNA: PNA & XNA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4161/adna.17086","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
摘要
Li et al. 2011(1)最近发表在《科学》杂志上的一篇论文报道了人类转录组中rna及其编码基因之间广泛存在的序列差异，称为RNA-DNA差异(rdd)。这一发现可能会给基因表达增加一层新的复杂性，但这项研究受到了批评。
A recent paper in Science by Li et al. 2011(1) reports widespread sequence differences in the human transcriptome between RNAs and their encoding genes termed RNA-DNA differences (RDDs). The findings could add a new layer of complexity to gene expression but the study has been criticized.
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