来自指根(Boesenbergia rotunda)成分的新型登革热竞争性Den2 Ns2b/Ns3抑制剂的片段分子设计

Q2 Medicine

In Silico Biology Pub Date : 2011-01-01 DOI:10.3233/ISB-2012-0442

Neni Frimayanti, Sharifuddin M Zain, Vannajan Sanghiran Lee, Habibah A Wahab, Rohana Yusof, Noorsaadah Abd Rahman

{"title":"来自指根(Boesenbergia rotunda)成分的新型登革热竞争性Den2 Ns2b/Ns3抑制剂的片段分子设计","authors":"Neni Frimayanti, Sharifuddin M Zain, Vannajan Sanghiran Lee, Habibah A Wahab, Rohana Yusof, Noorsaadah Abd Rahman","doi":"10.3233/ISB-2012-0442","DOIUrl":null,"url":null,"abstract":"Neni Frimayanti, Sharifuddin M. Zain, Vannajan Sanghiran Lee, Habibah A. Wahab, Rohana Yusof and Noorsaadah Abd. Rahmana,∗ Department of Chemistry, Faculty of Science, University of Malaya Lembah Pantai, Kuala Lumpur, Malaysia Computational Simulation and Modeling Laboratory, Department of Chemistry and Center for Innovation in Chemistry, Chiang Mai University, Bangkok, Thailand Pharmaceutical Design and Simulation Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia Department of Molecular Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia","PeriodicalId":39379,"journal":{"name":"In Silico Biology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/ISB-2012-0442","citationCount":"13","resultStr":"{\"title\":\"Fragment-based molecular design of new competitive dengue Den2 Ns2b/Ns3 inhibitors from the components of fingerroot (Boesenbergia rotunda).\",\"authors\":\"Neni Frimayanti, Sharifuddin M Zain, Vannajan Sanghiran Lee, Habibah A Wahab, Rohana Yusof, Noorsaadah Abd Rahman\",\"doi\":\"10.3233/ISB-2012-0442\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Neni Frimayanti, Sharifuddin M. Zain, Vannajan Sanghiran Lee, Habibah A. Wahab, Rohana Yusof and Noorsaadah Abd. Rahmana,∗ Department of Chemistry, Faculty of Science, University of Malaya Lembah Pantai, Kuala Lumpur, Malaysia Computational Simulation and Modeling Laboratory, Department of Chemistry and Center for Innovation in Chemistry, Chiang Mai University, Bangkok, Thailand Pharmaceutical Design and Simulation Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia Department of Molecular Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia\",\"PeriodicalId\":39379,\"journal\":{\"name\":\"In Silico Biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3233/ISB-2012-0442\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"In Silico Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3233/ISB-2012-0442\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"In Silico Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3233/ISB-2012-0442","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 13

摘要

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Fragment-based molecular design of new competitive dengue Den2 Ns2b/Ns3 inhibitors from the components of fingerroot (Boesenbergia rotunda).

Neni Frimayanti, Sharifuddin M. Zain, Vannajan Sanghiran Lee, Habibah A. Wahab, Rohana Yusof and Noorsaadah Abd. Rahmana,∗ Department of Chemistry, Faculty of Science, University of Malaya Lembah Pantai, Kuala Lumpur, Malaysia Computational Simulation and Modeling Laboratory, Department of Chemistry and Center for Innovation in Chemistry, Chiang Mai University, Bangkok, Thailand Pharmaceutical Design and Simulation Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia Department of Molecular Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

In Silico Biology Computer Science-Computational Theory and Mathematics

CiteScore

2.20

自引率

0.00%

发文量

期刊介绍： The considerable "algorithmic complexity" of biological systems requires a huge amount of detailed information for their complete description. Although far from being complete, the overwhelming quantity of small pieces of information gathered for all kind of biological systems at the molecular and cellular level requires computational tools to be adequately stored and interpreted. Interpretation of data means to abstract them as much as allowed to provide a systematic, an integrative view of biology. Most of the presently available scientific journals focus either on accumulating more data from elaborate experimental approaches, or on presenting new algorithms for the interpretation of these data. Both approaches are meritorious.