药用水蛭消化道内的先天免疫和后天免疫

IF 1.2 4区农林科学 Q4 IMMUNOLOGY

ISJ-Invertebrate Survival Journal Pub Date : 2011-01-01 Epub Date: 2011-08-29

Ac Silver, J Graf

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引用次数: 0

摘要

特别是当与独特的生物适应性相结合时，无脊椎动物为先天免疫提供了重要的见解，因为免疫反应不受脊椎动物进化的适应性免疫的影响。其中一个例子是药用水蛭蛭蛭的消化道，它在两个方面是不寻常的，它包含一个简单的微生物群落，它储存了大量的脊椎动物血液，可以保存几个月。在这篇综述中，我们将讨论水蛭的先天免疫和从摄入的血液中获得的免疫，我们称之为获得性免疫，以区分它与水蛭基因组编码的免疫。

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Innate and procured immunity inside the digestive tract of the medicinal leech.

Especially when combined with unique biological adaptations, invertebrate animals provide important insights into innate immunity because the immune response is not complicated by adaptive immunity that vertebrates evolved. One such example is the digestive tract of the medicinal leech, Hirudo verbana, which is unusual in two aspects, it contains a simple microbial community and it stores large amounts of vertebrate blood for a several months. In this review we will discuss aspects of the innate immunity of the leech and from the ingested blood that we term procured immunity to differentiate it from the immunity encoded by the leech genome.

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来源期刊

ISJ-Invertebrate Survival Journal IMMUNOLOGY-ZOOLOGY

CiteScore

2.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Invertebrate Survival Journal (ISJ) is an international and open access journal devoted to prompt and innovative studies on the basic defense mechanisms in invertebrates, in particular with a view to identifying biotechnologies able to act against derived diseases and related economic damage. Contributions will be mainly in the form of Letters to the Editor, Visions and Perspectives, Short Communications, Technical Reports, Research Reports, Review, Minireview and Reports of Meetings. Letters to the Editor can be commentaries or perspectives on invertebrate defence mechanisms or replies to the data published in ISJ.