皮肤病变,多发性关节炎,抗核抗体阳性的女孩。

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-04-04 DOI:10.5402/2011/657673
Jorge L Musuruana, Javier A Cavallasca
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引用次数: 0

摘要

1996年10月,一名14岁女孩因皮肤损伤、虚弱和关节痛而入院。检查发现,无瘢痕性毛发稀疏,额发际线上方部分变宽,面部、颈部、手臂和躯干出现多形态丘疹状鳞状皮疹,腿部出现网状活斑。口腔及鼻黏膜出现多处溃疡。多关节炎累及手腕、掌指关节、近端指间关节和手脚跖指关节。面部皮肤活检符合亚急性皮肤红斑狼疮。患者开始使用强的松60mg /d,未见改善,随后加用盐酸氯喹6mg /kg/d,连用一年。皮肤损伤几乎愈合,只剩下色素沉着的斑点。在过去的14年里,她没有表现出任何皮肤或全身症状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A girl with cutaneous lesions, polyarthritis, and antinuclear antibodies positivity.

A girl with cutaneous lesions, polyarthritis, and antinuclear antibodies positivity.

A girl with cutaneous lesions, polyarthritis, and antinuclear antibodies positivity.

A girl with cutaneous lesions, polyarthritis, and antinuclear antibodies positivity.

On October 1996, a 14-year-old girl was admitted to the hospital because cutaneous lesions, asthenia, and arthralgias. On examination, there was nonscarring hair thinning with a widened part over the frontal hairline, polymorphic papulosquamous rash on her face, neck, arms, and trunk, and livedo reticularis in her legs. Multiple aphtous ulcers were present on the buccal and nasal mucosa. There was polyarthritis involving the wrist, metacarpophalangeal joints, proximal interphalangeal joints, and metatarsophalangeal joints of both hands and feet. Skin biopsy of the face was compatible with subacute cutaneous lupus erythematosus. She started on prednisone 60 mg/d without improvement, and later hdroxhchloroquine (HCQ) 6 mg/kg/d was added for one year. Cutaneous lesions were almost healed, with just a hypopigmented macules left. Over the last 14 years, she has not shown any cutaneous or systemic manifestations.

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