寡核苷酸合成及基因合成专利。

Tingsheng Yu, Xiao Bao, Wenxian Piao, Jingli Peng, Wei Li, Cui Yang, Meng Xing, Yiliu Zhang, Jinhuan Qi, Lei Xu, Li Xu, Qiuyun Liu
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引用次数: 4

摘要

基因合成是一个新兴的领域,在合成生物学和分子生物学中有着广泛的应用。该领域不断发展,导致寡核苷酸合成和基因合成技术的关键进展,具有简单,成本效益和高通量。小型化、多路复用、微流控处理和集成微芯片工程将在不影响DNA合成保真度的前提下降低成本和提高生产率,而海量的基因组信息为合成生物学提供了无限的DNA元件和基因原料来源。本文介绍了近年来在寡核苷酸合成和基因合成方面的一些专利。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent patents on oligonucleotide synthesis and gene synthesis.

Gene synthesis is an emerging field which has widespread implications in synthetic biology and molecular biology. The field is constantly evolving which has led to key advances in oligonucleotide synthesis and gene synthesis technologies, with simplicity, cost effectiveness and high throughput. The miniaturization, multiplexing, microfluidic processing and the integrated microchip engineering will drive down cost and increase productivity without compromising DNA synthesis fidelity, whereas the gigantic amount of genome information provides infinite source of DNA elements and genes as raw material for synthetic biology. This article describes some of the recent patents on oligonucleotide synthesis and gene synthesis.

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