{"title":"用于联合治疗的纳米药物制剂。","authors":"Twan Lammers, Gert Storm, Fabian Kiessling","doi":"10.3402/nano.v1i0.5705","DOIUrl":null,"url":null,"abstract":"Nanomedicine formulations are nanometer-sized carrier materials designed for improving the biodistribution of systemically applied (chemo-) therapeutic drugs. Clinically relevant examples of nanomedicine formulations are liposomes, polymers and micelles. By delivering pharmacologically active agents more selectively to pathological sites (site-specific drug delivery) and/or by guiding them away from potentially endangered healthy tissues (site-avoidance drug delivery), nanomedicine formulations aim to improve the balance between the efficacy and the toxicity of therapeutic interventions. (Published: 8 November 2010) Citation: Nano Reviews 2010, 1 : 5705 - DOI: 10.3402/nano.v1i0.5705","PeriodicalId":74237,"journal":{"name":"Nano reviews","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/nano.v1i0.5705","citationCount":"15","resultStr":"{\"title\":\"Nanomedicine formulations for combination therapies.\",\"authors\":\"Twan Lammers, Gert Storm, Fabian Kiessling\",\"doi\":\"10.3402/nano.v1i0.5705\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nanomedicine formulations are nanometer-sized carrier materials designed for improving the biodistribution of systemically applied (chemo-) therapeutic drugs. Clinically relevant examples of nanomedicine formulations are liposomes, polymers and micelles. By delivering pharmacologically active agents more selectively to pathological sites (site-specific drug delivery) and/or by guiding them away from potentially endangered healthy tissues (site-avoidance drug delivery), nanomedicine formulations aim to improve the balance between the efficacy and the toxicity of therapeutic interventions. (Published: 8 November 2010) Citation: Nano Reviews 2010, 1 : 5705 - DOI: 10.3402/nano.v1i0.5705\",\"PeriodicalId\":74237,\"journal\":{\"name\":\"Nano reviews\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3402/nano.v1i0.5705\",\"citationCount\":\"15\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nano reviews\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3402/nano.v1i0.5705\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2010/11/8 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nano reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3402/nano.v1i0.5705","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2010/11/8 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Nanomedicine formulations for combination therapies.
Nanomedicine formulations are nanometer-sized carrier materials designed for improving the biodistribution of systemically applied (chemo-) therapeutic drugs. Clinically relevant examples of nanomedicine formulations are liposomes, polymers and micelles. By delivering pharmacologically active agents more selectively to pathological sites (site-specific drug delivery) and/or by guiding them away from potentially endangered healthy tissues (site-avoidance drug delivery), nanomedicine formulations aim to improve the balance between the efficacy and the toxicity of therapeutic interventions. (Published: 8 November 2010) Citation: Nano Reviews 2010, 1 : 5705 - DOI: 10.3402/nano.v1i0.5705
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