5-氟尿嘧啶输注致冠心病患者心绞痛1例。

Reza Tajik, Habib Saadat, Maryam Taherkhani, Mohammad Reza Movahed
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引用次数: 15

摘要

本文综述了5-氟尿嘧啶(5-FU)治疗无明显冠状动脉病变患者心绞痛的发生情况。我们提出一个案例,然后回顾文献。43岁男性,有结肠癌病史,在静脉输注5-FU时发生典型心绞痛。心绞痛发作时心电图显示高T波。在第二次5-FU输注期间,心绞痛和心电图改变再次发生。他的冠状动脉造影正常。该病例与罕见的5- fu诱发心绞痛一致,尽管冠状动脉正常。医生应该意识到5-FU输注的这一重要副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Angina induced by 5-fluorouracil infusion in a patient with normal coronaries.

This article reviews the occurrence of angina in patients treated with 5-fluorouracil (5-FU) without significant coronary artery disease. We present a case followed by a review of the literature. A 43-year-old man with a history of colon cancer developed typical angina during intravenous infusion of 5-FU. His electrocardiogram (ECG) showed tall T waves during his angina episode. His angina and ECG changes reoccurred during a second 5-FU infusion. His coronary angiography was normal. This case is consistent with a rare occurrence of 5-FU-induced angina despite normal coronaries. Physician should be aware of this important side effect of 5-FU infusion.

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