优化诊断和治疗坏死性外耳炎是必要的。

Danish medical bulletin Pub Date : 2011-07-01
Kirse Bock, Therese Ovesen
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引用次数: 0

摘要

坏死性外耳炎(NEO)是外耳道和颞骨的一种破坏性和危及生命的感染。本文的目的是评估NEO的诊断和治疗,并推荐新的指南。材料和方法:从2000年1月1日至2009年12月31日,回顾性纳入11例患者,代码DH609,无规范。回顾记录:年龄、症状、临床表现、合并症、影像学、微生物学和治疗。结果:患者年龄中位数为75岁,住院治疗中位数为6.3个月。所有患者都属于危险组。发现诊断延误导致疾病进一步发展。与目前的国际建议相反,治疗主要包括局部抗生素与手术相结合。所有患者都活了下来,但大多数患者都留下了听力损失和精神问题。结论:建议提高对诊断标准的认识,并根据国际概念从局部抗生素转向环丙沙星长期系统单药治疗。手术应留给广泛和难治性病例。提出了诊断标准和治疗指南。资金:无关紧要。试验注册:不相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimised diagnosis and treatment of necrotizing external otitis is warranted.

Introduction: Necrotizing external otitis (NEO) is a devastating and life-threatening infection in the external auditory canal and the temporal bone. The aim of this paper is to evaluate the diagnostics and treatment of NEO and to recommend new guidelines.

Material and methods: Eleven patients were retrospectively enrolled under the code DH609 otitis externa without specification from 1 January 2000 to 31 December 2009. Records were reviewed to register: age, symptoms, clinical findings, comorbidity, imaging, microbiology and treatment.

Results: The median age was 75 years and the median time of therapy at the hospital was 6.3 months. All patients belonged to a risk group. A diagnostic delay was found resulting in further progression of the disease. In contrast to current international recommendations, the treatment consisted mostly of local antibiotics in combination with surgery. All patients survived, but most patients were left with hearing loss and psychiatric problems.

Conclusion: A greater awareness of diagnostic criteria and a shift from local antibiotics to prolonged systemic monotherapy with ciprofloxacin in accordance with international concepts is recommended. Surgery should be left for extensive and refractory cases only. A list of diagnostic criteria and treatment guidelines is presented.

Funding: Not relevant.

Trial registration: Not relevant.

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Danish medical bulletin
Danish medical bulletin 医学-医学:内科
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