儿童交替偏瘫:托吡酯和氟桂利嗪成功治疗1例。

R Aishworiya, P S Low, S K H Tay
{"title":"儿童交替偏瘫:托吡酯和氟桂利嗪成功治疗1例。","authors":"R Aishworiya,&nbsp;P S Low,&nbsp;S K H Tay","doi":"10.1179/1465328111Y.0000000007","DOIUrl":null,"url":null,"abstract":"<p><p>Alternating hemiplegia of childhood (AHC) is a rare neurological disorder which usually presents before 18 months of age and is characterised by recurrent alternating episodes of hemiparesis. A single effective treatment for this condition is yet to be established; flunarizine is currently the most widely used but with varying degrees of success. An 18-month-old child presented with AHC and treatment with a combination of topiramate and flunarizine made a significant difference in controlling the frequency and severity of the attacks. This possibly allowed a better developmental outcome than in most children with this condition. Topiramate combined with flunarizine for treating AHC has much potential for further research.</p>","PeriodicalId":50759,"journal":{"name":"Annals of Tropical Paediatrics","volume":"31 2","pages":"149-52"},"PeriodicalIF":0.0000,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/1465328111Y.0000000007","citationCount":"5","resultStr":"{\"title\":\"Alternating hemiplegia of childhood: successful treatment with topiramate and flunarizine, a case report.\",\"authors\":\"R Aishworiya,&nbsp;P S Low,&nbsp;S K H Tay\",\"doi\":\"10.1179/1465328111Y.0000000007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Alternating hemiplegia of childhood (AHC) is a rare neurological disorder which usually presents before 18 months of age and is characterised by recurrent alternating episodes of hemiparesis. A single effective treatment for this condition is yet to be established; flunarizine is currently the most widely used but with varying degrees of success. An 18-month-old child presented with AHC and treatment with a combination of topiramate and flunarizine made a significant difference in controlling the frequency and severity of the attacks. This possibly allowed a better developmental outcome than in most children with this condition. Topiramate combined with flunarizine for treating AHC has much potential for further research.</p>\",\"PeriodicalId\":50759,\"journal\":{\"name\":\"Annals of Tropical Paediatrics\",\"volume\":\"31 2\",\"pages\":\"149-52\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1179/1465328111Y.0000000007\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Tropical Paediatrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1179/1465328111Y.0000000007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Tropical Paediatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1179/1465328111Y.0000000007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5

摘要

儿童交替偏瘫(AHC)是一种罕见的神经系统疾病,通常在18个月前出现,其特征是反复交替发作的偏瘫。目前还没有一种单一有效的治疗方法;氟桂利嗪是目前使用最广泛的药物,但取得了不同程度的成功。一名18个月大的儿童出现AHC,托吡酯和氟桂利嗪联合治疗在控制发作频率和严重程度方面有显著差异。这可能比大多数患有这种疾病的儿童有更好的发展结果。托吡酯联合氟桂利嗪治疗AHC有进一步研究的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alternating hemiplegia of childhood: successful treatment with topiramate and flunarizine, a case report.

Alternating hemiplegia of childhood (AHC) is a rare neurological disorder which usually presents before 18 months of age and is characterised by recurrent alternating episodes of hemiparesis. A single effective treatment for this condition is yet to be established; flunarizine is currently the most widely used but with varying degrees of success. An 18-month-old child presented with AHC and treatment with a combination of topiramate and flunarizine made a significant difference in controlling the frequency and severity of the attacks. This possibly allowed a better developmental outcome than in most children with this condition. Topiramate combined with flunarizine for treating AHC has much potential for further research.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Annals of Tropical Paediatrics
Annals of Tropical Paediatrics 医学-热带医学
自引率
0.00%
发文量
0
审稿时长
>12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信