[多重耐药病原体感染]。

Anestezjologia intensywna terapia Pub Date : 2010-04-01
Urszula Zielińska-Borkowska, Małgorzata Złotorowicz
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引用次数: 0

摘要

背景:强化治疗单位是病原体容易传播的地方。不适当的抗生素治疗有助于产生称为多重耐药、广泛耐药或普遍耐药的新菌株。对于国际电联患者来说,这类病原体特别危险。病例报告:病例50岁的男子诊断为感染性休克,反复手术后,由于Vater壶腹肿瘤被描述。在血液和腹膜液培养中,首先分离出阴沟肠杆菌ESBL和肺炎克雷伯菌;检出鲍曼不动杆菌。靶向抗生素治疗并没有带来预期的效果。第5天开始使用替加环素和亚胺培南,并持续10天以上。经过4天的联合治疗,细菌菌株被根除。病人被送往转诊病房,情况良好。结论:亚胺培南联合新抗生素替加环素是治疗腹腔感染感染性休克的有效方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Infection with multidrug-resistant pathogens].

Background: Intensive therapy units are the places where pathogens can easily spread. Improper antibiotic therapy contributes to the selection of new strains called multidrug-resistant, extensively drug-resistant or pandrug-resistant. For ITU patients, such pathogens are particularly dangerous.

Case report: The case of a 50-year-old man diagnosed with septic shock after repeated surgeries due to Vater's ampulla tumour was described. In blood and peritoneal fluid cultures, Enterobacter cloacae ESBL and Klebsiella pneumoniae were first isolated; then Acinetobacter baumannii was also detected. The targeted antibiotic therapy instituted did not bring the expected results. On day 5, tigecycline and imipenem were started and continued over 10 days. After 4 days of combined therapy, bacterial strains were eradicated. The patient was sent to the referring ward in good condition.

Conclusion: Combined use of imipenem and a new antibiotic - tigecycline provides effective treatment of septic shock in the course of intra-abdominal infection.

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