[非管制精神药物药物设计与生物活性预测的计算研究]。

Q4 Medicine

Bulletin of National Institute of Health Sciences Pub Date : 2010-01-01

Masaaki Kurihara

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引用次数: 0

摘要

我们设计和合成了突变型维生素D受体激动剂(Arg274Leu)的救援配体，并通过计算机模拟进行了非管制精神药物的QSAR研究和未经批准或未经授权的药物-人磷酸二酯酶5 (PDE5)抑制剂的对接研究。

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本刊更多论文

[Computational study on drug design and prediction of bioactivity for regulation of non-controlled psychotropic substances].

We demonstrated design and synthesis of rescue ligands for agonists of the mutant vitamin D receptor (Arg274Leu), and performed QSAR study of non-controlled psychotropic substances and docking study of non-approved or unauthorized pharmaceuticals, inhibitors of human phosphodiesterase 5 (PDE5) using computer simulation.

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来源期刊

Bulletin of National Institute of Health Sciences Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量