[非洲儿童镰状细胞性骨髓炎的流行病学、诊断和管理方面]。

Sante (Montrouge, France) Pub Date : 2010-10-01 Epub Date: 2011-02-15 DOI:10.1684/san.2010.0212
Faustin Félicien Mouafo Tambo, Marcellin Ngowe Ngowe, Ondobo Gervais Andze, Maurice Aurélien Sosso
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引用次数: 2

摘要

儿童镰状细胞性骨髓炎是镰状细胞病骨性关节炎的并发症之一。目的了解非洲儿童镰状细胞性骨髓炎的流行病学、诊断和治疗情况,以提高治疗水平。工具和方法对记录的回顾显示,从2004年4月到2009年9月,在雅温得妇女和儿童医院的外科和儿科治疗了11例携带镰状细胞特征的0至15岁儿童骨髓炎。结果患儿平均年龄为7岁,以1 ~ 5岁发生率最高。男女比例是2:1。只有30%的病例发现了进入门户。该病对长骨、非瘘管型、纯合子型和沙门氏菌频率的偏爱都是显著的。医疗和预防性治疗始终适用,其次是矫形治疗。另一方面,手术的有用性是有争议的。80%的病例获得了愈合。结论作者描述了非洲镰状细胞病儿童骨髓炎的概况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Aspects of the epidemiology, diagnosis and management of sickle cell osteomyelitis in children in Africa].

IntroductionSickle cell osteomyelitis in children is one of the complications of osteoarthritis in sickle cell disease.ObjectiveTo describe the epidemiology, diagnosis and treatment of sickle cell osteomyelitis in children in Africa to improve management.Tools and methodA review of records showed that from April 2004 through September 2009, eleven cases of osteomyelitis in children aged 0 to 15 years who carried the sickle cell trait were treated in the surgical and pediatric unit of the Women's and Children's Hospital of Yaounde.ResultThe children's mean age was 7 years, but frequency was highest for those aged 1 to 5 years. The sex ratio was 2:1 male. The portal of entry was found for only 30% of cases. The predilection of the disease for long bones, the non-fistulated forms, the homozygous type, and the frequency of Salmonella were all remarkable. Medical and preventive treatment, always applied, were followed by orthopedic treatment. The usefulness of surgery, on the other hand, is subject to debate. Healing was obtained in 80% of cases.ConclusionThe authors describe the profile of osteomyelitis in children with sickle cell disease in Africa.

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