Irshad-Ur Rehman, Muhammad Idrees, Muhammad Ali, Liaqat Ali, Sadia Butt, Abrar Hussain, Haji Akbar, Samia Afzal
{"title":"具有不同起源的基因型3a型丙型肝炎病毒在巴基斯坦流行。","authors":"Irshad-Ur Rehman, Muhammad Idrees, Muhammad Ali, Liaqat Ali, Sadia Butt, Abrar Hussain, Haji Akbar, Samia Afzal","doi":"10.1186/1479-0556-9-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hepatitis C virus (HCV) is one of the leading causes of viral hepatitis worldwide and its genotype 3a is predominant in vast areas of Pakistan.</p><p><strong>Findings: </strong>The present study reports the first full sequence of HCV 3a isolate PK-1 from Pakistan. This nucleotide sequence was compared with six other HCV genotype 3a full length sequences from different regions of the world by using statistical methods of phylogenetic analysis.</p><p><strong>Conclusion: </strong>The nucleotide difference of these seven sequences shows that HCV genotype 3a of phylogenetically distinct origin is circulating in Pakistan.</p>","PeriodicalId":12596,"journal":{"name":"Genetic Vaccines and Therapy","volume":"9 1","pages":"2"},"PeriodicalIF":0.0000,"publicationDate":"2011-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1479-0556-9-2","citationCount":"32","resultStr":"{\"title\":\"Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan.\",\"authors\":\"Irshad-Ur Rehman, Muhammad Idrees, Muhammad Ali, Liaqat Ali, Sadia Butt, Abrar Hussain, Haji Akbar, Samia Afzal\",\"doi\":\"10.1186/1479-0556-9-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Hepatitis C virus (HCV) is one of the leading causes of viral hepatitis worldwide and its genotype 3a is predominant in vast areas of Pakistan.</p><p><strong>Findings: </strong>The present study reports the first full sequence of HCV 3a isolate PK-1 from Pakistan. This nucleotide sequence was compared with six other HCV genotype 3a full length sequences from different regions of the world by using statistical methods of phylogenetic analysis.</p><p><strong>Conclusion: </strong>The nucleotide difference of these seven sequences shows that HCV genotype 3a of phylogenetically distinct origin is circulating in Pakistan.</p>\",\"PeriodicalId\":12596,\"journal\":{\"name\":\"Genetic Vaccines and Therapy\",\"volume\":\"9 1\",\"pages\":\"2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-01-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1186/1479-0556-9-2\",\"citationCount\":\"32\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Genetic Vaccines and Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/1479-0556-9-2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Genetic Vaccines and Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/1479-0556-9-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan.
Background: Hepatitis C virus (HCV) is one of the leading causes of viral hepatitis worldwide and its genotype 3a is predominant in vast areas of Pakistan.
Findings: The present study reports the first full sequence of HCV 3a isolate PK-1 from Pakistan. This nucleotide sequence was compared with six other HCV genotype 3a full length sequences from different regions of the world by using statistical methods of phylogenetic analysis.
Conclusion: The nucleotide difference of these seven sequences shows that HCV genotype 3a of phylogenetically distinct origin is circulating in Pakistan.
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