Nienke Vrisekoop, Judith N Mandl, Ronald N Germain
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Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.
Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.