S O Sarr, A Diop, Y M Diop, B Ndiaye, Y M Koffi, D Fall, A Smine
{"title":"[控制塞内加尔使用的抗逆转录病毒药物的质量]。","authors":"S O Sarr, A Diop, Y M Diop, B Ndiaye, Y M Koffi, D Fall, A Smine","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Success of any program to fight AIDS passes through out quality of antiretroviral medicines. The control and follow-up of the quality of these medicines constitute essential levers to guarantee quality. Our study aims to evaluate the quality of antiretroviral medicines used in Senegal by means of a mini laboratory from the German Pharmaceutical Health Fund.</p><p><strong>Materials and methods: </strong>The mini laboratory provides technical arsenal necessary for the analysis. To sum up, 43 samples of antiretroviral medicines have been submitted to three types of simple, quick and reliable tests which are physical and visual inspection, disintegration and thin layer chromatography.</p><p><strong>Results: </strong>The obtained results give at physical and visual inspection, 9.3% of samples which are not similar. 30 samples out of 32 have a good disintegration time. About 11.6% of samples are not similar to thin layer chromatography.</p><p><strong>Conclusion: </strong>The control of the quality of antiretroviral medicines is necessary if we consider the number of no conform cases which are relatively important. The mini laboratory can constitute an interesting tool for technical control facilities in developing countries that suffer from a real lack of materials.</p>","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"53 3","pages":"220-7"},"PeriodicalIF":0.0000,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Control of the quality of antiretroviral medicines used in Senegal].\",\"authors\":\"S O Sarr, A Diop, Y M Diop, B Ndiaye, Y M Koffi, D Fall, A Smine\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Success of any program to fight AIDS passes through out quality of antiretroviral medicines. The control and follow-up of the quality of these medicines constitute essential levers to guarantee quality. Our study aims to evaluate the quality of antiretroviral medicines used in Senegal by means of a mini laboratory from the German Pharmaceutical Health Fund.</p><p><strong>Materials and methods: </strong>The mini laboratory provides technical arsenal necessary for the analysis. To sum up, 43 samples of antiretroviral medicines have been submitted to three types of simple, quick and reliable tests which are physical and visual inspection, disintegration and thin layer chromatography.</p><p><strong>Results: </strong>The obtained results give at physical and visual inspection, 9.3% of samples which are not similar. 30 samples out of 32 have a good disintegration time. About 11.6% of samples are not similar to thin layer chromatography.</p><p><strong>Conclusion: </strong>The control of the quality of antiretroviral medicines is necessary if we consider the number of no conform cases which are relatively important. The mini laboratory can constitute an interesting tool for technical control facilities in developing countries that suffer from a real lack of materials.</p>\",\"PeriodicalId\":75773,\"journal\":{\"name\":\"Dakar medical\",\"volume\":\"53 3\",\"pages\":\"220-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dakar medical\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dakar medical","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Control of the quality of antiretroviral medicines used in Senegal].
Introduction: Success of any program to fight AIDS passes through out quality of antiretroviral medicines. The control and follow-up of the quality of these medicines constitute essential levers to guarantee quality. Our study aims to evaluate the quality of antiretroviral medicines used in Senegal by means of a mini laboratory from the German Pharmaceutical Health Fund.
Materials and methods: The mini laboratory provides technical arsenal necessary for the analysis. To sum up, 43 samples of antiretroviral medicines have been submitted to three types of simple, quick and reliable tests which are physical and visual inspection, disintegration and thin layer chromatography.
Results: The obtained results give at physical and visual inspection, 9.3% of samples which are not similar. 30 samples out of 32 have a good disintegration time. About 11.6% of samples are not similar to thin layer chromatography.
Conclusion: The control of the quality of antiretroviral medicines is necessary if we consider the number of no conform cases which are relatively important. The mini laboratory can constitute an interesting tool for technical control facilities in developing countries that suffer from a real lack of materials.
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