ONTARGET、TRANSCEND和PRoFESS:新发糖尿病、心房颤动和左室肥厚。

Journal of hypertension. Supplement : official journal of the International Society of Hypertension Pub Date : 2009-06-01 DOI:10.1097/01.hjh.0000354519.67451.96

Ulrich Kintscher

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引用次数: 16

摘要

预防糖尿病是当前降低心血管风险策略的一个重要治疗目标。肾素-血管紧张素系统的阻断已被证明可以显著降低不同患者群体中新发糖尿病的发病率。本文将讨论血管紧张素- ii受体阻滞剂替米沙坦治疗新发糖尿病、心房颤动和左心室萎缩的三个大型临床终点试验的最新结果。

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ONTARGET, TRANSCEND, and PRoFESS: new-onset diabetes, atrial fibrillation, and left ventricular hypertrophy.

Prevention of diabetes represents an important therapeutic goal in current cardiovascular risk reduction strategies. Blockade of the renin-angiotensin system has been shown to markedly reduce the incidence of new-onset diabetes in different patient populations. Recent results from three large clinical endpoint trials with the angiotensin-II receptor blocker telmisartan regarding new-onset diabetes, atrial fibrillation, and left ventricular hypotrophy will be discussed.

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Journal of hypertension. Supplement : official journal of the International Society of Hypertension

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