绿色、无溶剂、非均相催化下的KA2偶联反应

IF 5.062

Journal of Molecular Catalysis A: Chemical Pub Date : 2017-01-01 DOI:10.1016/j.molcata.2016.09.028

Giovanna Bosica, Roderick Abdilla

{"title":"绿色、无溶剂、非均相催化下的KA2偶联反应","authors":"Giovanna Bosica, Roderick Abdilla","doi":"10.1016/j.molcata.2016.09.028","DOIUrl":null,"url":null,"abstract":"<div><p>Amberlyst A-21 supported CuI was found to be highly efficient novel heterogeneous catalyst for the three-component reaction between ketones, amines and alkynes, commonly called KA<sup>2</sup>-coupling. This inexpensive, easy-to-prepare, simple and recyclable catalyst has been employed in solventless conditions in the KA<sup>2</sup> coupling reaction involving both primary and secondary amines, ketones and various alkynes. The secondary and tertiary propargylamine products were obtained in good to excellent results in moderate reaction times.</p></div>","PeriodicalId":370,"journal":{"name":"Journal of Molecular Catalysis A: Chemical","volume":"426 ","pages":"Pages 542-549"},"PeriodicalIF":5.0620,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.molcata.2016.09.028","citationCount":"31","resultStr":"{\"title\":\"The KA2 coupling reaction under green, solventless, heterogeneous catalysis\",\"authors\":\"Giovanna Bosica, Roderick Abdilla\",\"doi\":\"10.1016/j.molcata.2016.09.028\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Amberlyst A-21 supported CuI was found to be highly efficient novel heterogeneous catalyst for the three-component reaction between ketones, amines and alkynes, commonly called KA<sup>2</sup>-coupling. This inexpensive, easy-to-prepare, simple and recyclable catalyst has been employed in solventless conditions in the KA<sup>2</sup> coupling reaction involving both primary and secondary amines, ketones and various alkynes. The secondary and tertiary propargylamine products were obtained in good to excellent results in moderate reaction times.</p></div>\",\"PeriodicalId\":370,\"journal\":{\"name\":\"Journal of Molecular Catalysis A: Chemical\",\"volume\":\"426 \",\"pages\":\"Pages 542-549\"},\"PeriodicalIF\":5.0620,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.molcata.2016.09.028\",\"citationCount\":\"31\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Molecular Catalysis A: Chemical\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1381116916304009\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Molecular Catalysis A: Chemical","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1381116916304009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 31

摘要

Amberlyst A-21负载的CuI是一种高效的新型非均相催化剂，用于酮、胺和炔的三组分反应，通常称为ka2偶联。该催化剂价格低廉、制备简单、可循环利用，在无溶剂条件下用于伯胺、仲胺、酮类和各种炔类的KA2偶联反应。在适当的反应时间内，得到了二级和三级丙胺产品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The KA2 coupling reaction under green, solventless, heterogeneous catalysis

查看原文本刊更多论文

The KA2 coupling reaction under green, solventless, heterogeneous catalysis

Amberlyst A-21 supported CuI was found to be highly efficient novel heterogeneous catalyst for the three-component reaction between ketones, amines and alkynes, commonly called KA²-coupling. This inexpensive, easy-to-prepare, simple and recyclable catalyst has been employed in solventless conditions in the KA² coupling reaction involving both primary and secondary amines, ketones and various alkynes. The secondary and tertiary propargylamine products were obtained in good to excellent results in moderate reaction times.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Molecular Catalysis A: Chemical 化学-物理化学

自引率

0.00%

发文量

审稿时长

2.8 months

期刊介绍： The Journal of Molecular Catalysis A: Chemical publishes original, rigorous, and scholarly full papers that examine the molecular and atomic aspects of catalytic activation and reaction mechanisms in homogeneous catalysis, heterogeneous catalysis (including supported organometallic catalysis), and computational catalysis.