甲状腺机能亢进和肾脏

Cathy E. Langston DVM, Dipl. ACVIM (Internal Medicine), Nyssa J. Reine DVM, Dipl. ACVIM (Internal Medicine)
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引用次数: 55

摘要

甲状腺机能亢进和慢性肾衰竭(CRF)都是老年猫的常见疾病。甲状腺机能亢进通过多种生理作用增加GFR。慢性肾功能衰竭可抑制伴有甲状腺功能亢进的猫的总T4浓度,游离T4并不是一个有用的鉴别试验。对于已有CRF的猫,建议使用药物治疗(如甲巯咪唑)。在接受甲状腺机能亢进治疗的猫中,大约30%出现明显的肾功能衰竭。它通常发生在治疗的一个月内,并且随着时间的推移往往保持温和和稳定。虽然GFR测量似乎是有用的,但没有实际的方法来预测哪些猫在甲状腺功能亢进治疗后会发生CRF。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hyperthyroidism and the Kidney

Hyperthyroidism and chronic renal failure (CRF) are both common diseases of older cats. Hyperthyroidism increases GFR by a variety of physiologic effects. Chronic renal failure can suppress total T4 concentrations in cats with concurrent hyperthyroidism, and free T4 is not a useful distinguishing test. Medical therapy (ie, methimazole) is recommended in cats with pre-existing CRF. Overt renal failure occurs in approximately 30% of cats treated for hyperthyroidism. It usually occurs within one month of treatment and tends to remain mild and stable over time. There is no practical way to predict which cats will develop CRF after treatment of hyperthyroidism, although GFR measurement does seem useful.

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