西地那非对日本患者视听性刺激(AVSS)试验的疗效

J Soh, Y Naya, S Ushijima, Y Naitoh, A Ochiai, Y Mizutani, A Kawauchi, T Miki, T Fujiwara
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引用次数: 3

摘要

在日本,西地那非对轻度至中度ED最有效,但对严重ED无效。为了评价西地那非的疗效,我们使用RigiScan Plus的AVSS测试进行了本研究。研究对象为56例ED患者(年龄34 ~ 82岁,平均60.5岁),分别在西地那非给药前后进行IIEF5问卷和AVSS测试。19例患者阴茎硬度无法测量。在这19例中,西地那非有效的有7例,无效的有12例。西地那非有效的7例均为假阴性。西地那非的敏感性为84%,特异性为100%。本研究提示RigiScan Plus的AVSS试验能够客观评价西地那非的疗效,并具有预测其疗效的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of sildenafil for Japanese patients with audio-visual sexual stimulation (AVSS) test by the RigiScan Plus.

Sildenafil is most effective in men with mild-to-moderate ED, but not severe ED in Japan. In order to evaluate the efficacy of sildenafil, we conducted the present study using the AVSS test by the RigiScan Plus. The subjects were 56 patients (age: 34-82 years, mean: 60.5 years) with ED. The IIEF5 questionnaire and the AVSS test were conducted before and after administration of sildenafil. The penile rigidity could not be measured in 19 patients. Of these 19, sildenafil was effective in 7 and not effective in 12. The 7 cases in whom sildenafil was effective were all false-negatives. The sensitivity of sildenafil was 84%, and its specificity was 100%. This study suggests that the AVSS test by RigiScan Plus can objectively evaluate the efficacy of sildenafil, and shows potential for predicting that efficacy.

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