[二酰基甘油酰基转移酶(DGAT)相关基因的研究进展]。

Hai-Ming Ma, Qi-Shun Shi, Xiao-Chun Liu
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引用次数: 0

摘要

二酰基甘油三酯酰基转移酶(DGAT)在生物体内不同组织的脂质形成中起着重要作用。DGAT催化三酰基甘油(TAG)生物合成的最后一步,将二酰基甘油(DAG)和脂肪酰基辅酶A (CoA)转化为三酰基甘油。这种酶由DGAT1和DGAT2编码。DGAT1属于胆固醇酰基转移酶(ACAT)基因家族。DGAT2属于单酰基甘油酰基转移酶(MGAT1)基因家族。本文综述了dgat相关基因的结构、在染色体上的定位及其生物学作用。并讨论了多态性与动物生产性能的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Progress in the study on diacylgycerol acyltransferase (DGAT)-related genes].

Diacylgycerol Acyltransferase (DGAT) plays an important role in the formation of lipid in different tissues of biological body. DGAT catalyzes the final step in triacylglycerol (TAG) biosynthesis by converting diacylgycerol (DAG) and fatty acyl-coenzyme A (CoA) into triacylglycerol. This enzyme is coded by both DGAT1 and DGAT2. DGAT1 belongs to the gene family of cholesterol acyltransferase (ACAT). DGAT2 belongs to the gene family of monoacylgycerol acyltransferases (MGAT1). This paper reviewed the structure, location on chromosome and biological effect of DGAT-related genes. The relationship between polymorphism and performance of animal was also discussed.

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