[来自1型糖尿病家庭的孩子]。

Renata Wasikowa, Dorota Suchańska, Danuta Suchańska, Aleksander Basiak, Anna Noczyńska, Teresa Stasińska
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引用次数: 0

摘要

1型糖尿病是观察个人与遗传易感性的疾病。观察到先天性缺陷的风险为3-5倍,因此1型糖尿病是已知致畸风险最高的因素之一。造成先天性缺陷的主要因素是高血糖症。观察到中枢神经系统、骨骼、泌尿和消化道的先天性缺陷。特点是巨大儿。观察到低钙血症、低镁血症、红细胞增多症、高胆红素血症、肥厚性心肌病、呼吸障碍。来自1型糖尿病家庭的儿童在新生儿时期患此病、其他疾病的风险很高。他们必须接受长期的医疗控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The child from families with type 1 diabetes].

Diabetes type 1 is observed in individuals with a genetic predisposition to the disease. Observed is a 3-5 fold risk for congenital defects, therefore diabetes type 1 is one of the highest known teratogenic risk factor. The main factor responsible for the development of congenital defects is hyperglycemia. Observed are congenital defects of the central nervous system, the bones, urinary and digestive tract. Characteristic is macrosomia. Observed are hypocalcemia, hypomagnesemia, polycythemia, hyperbilirubinemia, hypertrophic cardiomyopathy, respiratory disturbances. Children from families with diabetes type 1 are at high risk for the development of the disease in the newborn period, additional diseases. They must be in permanent medical control.

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