α-catenin从皮质心室区αE-catenin向中间区αN-catenin II的转换

Itsuki Ajioka , Kazunori Nakajima
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引用次数: 10

摘要

虽然已知钙粘蛋白和连环蛋白在神经发育过程中发挥重要作用,但α-连环蛋白在发育中的端脑中的类型仍不清楚。在这里,我们发现皮层的心室区(VZ)和神经节突起分别以互补的方式表达αE-catenin和αN-catenin。在皮层中,α-catenin由VZ区的αE-catenin转换为中间区(IMZ)的αN-catenin II。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Switching of α-catenin from αE-catenin in the cortical ventricular zone to αN-catenin II in the intermediate zone

Although cadherins and catenins are known to play important roles during neural development, the types of α-catenin present in the developing telencephalon are still unknown. Here, we show that the ventricular zones (VZ) of the cortex and the ganglionic eminences express αE-catenin and αN-catenin, respectively, in a complementary manner. In the cortex, α-catenin is switched from αE-catenin in the VZ to αN-catenin II in the intermediate zone (IMZ).

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