新型小鼠模型拓展了潜在的人类α细胞研究。

IF 1.9 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Islets Pub Date : 2021-07-04 Epub Date: 2021-04-14 DOI:10.1080/19382014.2021.1914507

Theodore Dos Santos, Patrick E MacDonald

引用次数: 0

摘要

保存GLP-1和GLP-2分泌的胰高血糖素敲除小鼠可以改善移植的人类胰岛和胰高血糖素反应的研究，为人类α-细胞和糖尿病研究提供前所未有的资源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Novel mouse model expands potential human α-cell research.

查看原文本刊更多论文

Novel mouse model expands potential human α-cell research.

A glucagon knock-out mouse with preserved GLP-1 and GLP-2 secretion allows for the improved study of transplanted human islets and glucagon responses- providing an unprecedented resource in human α-cell and diabetes research.

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来源期刊

Islets ENDOCRINOLOGY & METABOLISM-

CiteScore

3.30

自引率

4.50%

发文量

审稿时长

>12 weeks

期刊介绍： Islets is the first international, peer-reviewed research journal dedicated to islet biology. Islets publishes high-quality clinical and experimental research into the physiology and pathology of the islets of Langerhans. In addition to original research manuscripts, Islets is the leading source for cutting-edge Perspectives, Reviews and Commentaries. Our goal is to foster communication and a rapid exchange of information through timely publication of important results using print as well as electronic formats.