保持体形的挑战:核尺寸很重要。

IF 1.8 4区生物学 Q3 GENETICS & HEREDITY

Current Genetics Pub Date : 2021-08-01 Epub Date: 2021-03-29 DOI:10.1007/s00294-021-01176-1

Pallavi Deolal, Gurranna Male, Krishnaveni Mishra

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引用次数: 5

摘要

细胞器具有独特的形态，其大小与细胞大小之比是受调控的。细胞核是真核细胞中最重要的细胞器之一，通常呈圆形，占细胞体积的8-10%。众所周知，细胞核的形状和大小在细胞生长、分裂和某些应激过程中会经历重塑。核膜上蛋白质和脂质分布的调节对于保持核的形态和大小至关重要。由于大小和形态是相互联系的，改变其中一个会影响另一个。从这个角度来看，我们讨论了核的大小和形状调节之间的关系。

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The challenge of staying in shape: nuclear size matters.

Cellular organelles have unique morphology and the organelle size to cell size ratio is regulated. Nucleus is one of the most prominent, usually round in shape, organelle of a eukaryotic cell that occupies 8-10% of cellular volume. The shape and size of nucleus is known to undergo remodeling during processes such as cell growth, division and certain stresses. Regulation of protein and lipid distribution at the nuclear envelope is crucial for preserving the nuclear morphology and size. As size and morphology are interlinked, altering one influences the other. In this perspective, we discuss the relationship between size and shape regulation of the nucleus.

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来源期刊

Current Genetics 生物-遗传学

CiteScore

6.00

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： Current Genetics publishes genetic, genomic, molecular and systems-level analysis of eukaryotic and prokaryotic microorganisms and cell organelles. All articles are peer-reviewed. The journal welcomes submissions employing any type of research approach, be it analytical (aiming at a better understanding), applied (aiming at practical applications), synthetic or theoretical. Current Genetics no longer accepts manuscripts describing the genome sequence of mitochondria/chloroplast of a small number of species. Manuscripts covering sequence comparisons and analyses that include a large number of species will still be considered.