不变性自然杀伤T细胞的代谢:综述。

Immunometabolism Pub Date : 2021-01-01 Epub Date: 2021-02-10 DOI:10.20900/immunometab20210010
Emily L Yarosz, Cheong-Hee Chang, Ajay Kumar
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引用次数: 5

摘要

细胞代谢是产生细胞生长和生存所需的能量和大分子的关键。近年来,代谢在T细胞分化、增殖和功能调节中的重要性一直是研究的热点。然而,对不变性自然杀伤T细胞(iNKT)的代谢调节知之甚少。从这个角度来看,我们将讨论目前已知的iNKT细胞免疫代谢以及这些发现与CD4 T细胞的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Metabolism in Invariant Natural Killer T Cells: An Overview.

Metabolism in Invariant Natural Killer T Cells: An Overview.

Cellular metabolism is critical for generating energy and macromolecules for cell growth and survival. In recent years, the importance of metabolism in mediating T cell differentiation, proliferation, and function has been a hot topic of investigation. However, very little is known about metabolic regulation in invariant natural killer T (iNKT) cells. In this viewpoint, we will discuss what is currently known about immunometabolism in iNKT cells and how these findings relate to CD4 T cells.

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