{"title":"非人类灵长类动物和利什曼原虫免疫","authors":"Sonia André , Vasco Rodrigues , Morgane Picard , Ricardo Silvestre , Jérôme Estaquier","doi":"10.1016/j.cytox.2020.100038","DOIUrl":null,"url":null,"abstract":"<div><p>In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus <em>Leishmania</em> and classified as one of the neglected tropical diseases.</p></div>","PeriodicalId":37028,"journal":{"name":"Cytokine: X","volume":"2 4","pages":"Article 100038"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cytox.2020.100038","citationCount":"5","resultStr":"{\"title\":\"Non-human primates and Leishmania immunity\",\"authors\":\"Sonia André , Vasco Rodrigues , Morgane Picard , Ricardo Silvestre , Jérôme Estaquier\",\"doi\":\"10.1016/j.cytox.2020.100038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus <em>Leishmania</em> and classified as one of the neglected tropical diseases.</p></div>\",\"PeriodicalId\":37028,\"journal\":{\"name\":\"Cytokine: X\",\"volume\":\"2 4\",\"pages\":\"Article 100038\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.cytox.2020.100038\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cytokine: X\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2590153220300185\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cytokine: X","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2590153220300185","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by infection with protozoan parasites of the genus Leishmania and classified as one of the neglected tropical diseases.
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