商用SARS-CoV-2实时pcr检测的比较和相关性，爱尔兰，2020年6月。

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin Pub Date : 2021-02-01 DOI:10.2807/1560-7917.ES.2021.26.6.2002079

Anne Carroll, Eleanor McNamara

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引用次数: 12

摘要

我们报告了各种市售SARS-CoV-2 PCR试剂盒的性能，这些试剂盒在爱尔兰的几个不同地点使用，以确定不同平台的Ct值是否具有可比性。我们还研究了Ct值(在没有病毒培养的情况下计算病毒载量的替代值)是否可以用于排除SARS-CoV-2感染及其并发症。我们发现，对于相同的计算病毒载量，不同测定方法的Ct值存在差异;在解释结果时应考虑到这一点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Comparison and correlation of commercial SARS-CoV-2 real-time-PCR assays, Ireland, June 2020.

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Comparison and correlation of commercial SARS-CoV-2 real-time-PCR assays, Ireland, June 2020.

We report the performance of a variety of commercially available SARS-CoV-2 PCR kits, used in several different sites across Ireland to determine if C_t values across platforms are comparable. We also investigate whether a C_t value, a surrogate for calculated viral loads in the absence of viral culture of > 34 can be used to exclude SARS-CoV-2 infection and its complications. We found a variation in C_t values from different assays for the same calculated viral load; this should be taken into consideration for result interpretation.

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Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

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