奥氮平引起的体重增加和脂质和葡萄糖代谢紊乱。

Essential psychopharmacology Pub Date : 2005-01-01
Ursula eder-Ischia, Christoph Ebenbichler, W Wolfgang Fleischhacker
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引用次数: 0

摘要

在非典型抗精神病药物中,氯氮平和奥氮平已知会导致显著的体重增加。与喹硫平一起,它们可能会损害葡萄糖代谢,增加患2型糖尿病的风险。它们还与甘油三酯水平升高和冠状动脉疾病风险增加有关。临床医生在开这些抗精神病药物处方时应认真考虑这些风险,并在使用这些药物时采取明智的保护措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Olanzapine-induced weight gain and disturbances of lipid and glucose metabolism.

Among the atypical antipsychotics, clozapine and olanzapine are known to cause significant weight gain. Along with quetiapine, they may impair glucose metabolism and increase the risk for type 2 diabetes. They are also associated with a rise in triglyceride levels and an increased risk for coronary artery disease. Clinicians should take these risks seriously in prescribing these antipsychotics and employ intelligent safeguards if and when they use them.

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