人乳头瘤病毒16型(HPV 16) E6蛋白中CD8 t细胞表位的模式在HPV 16感染已无法检测到的年轻女性中

Mayumi Nakagawa, Kevin H Kim, Anna-Barbara Moscicki
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引用次数: 19

摘要

在清除了人乳头瘤病毒16感染的妇女中,检测了E6蛋白中识别的CD8 t细胞表位的模式。利用感染重组痘苗病毒的自体树突状细胞建立t细胞系。23名女性中有8名(34.8%)存在潜在抗原表位。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Patterns of CD8 T-cell epitopes within the human papillomavirus type 16 (HPV 16) E6 protein among young women whose HPV 16 infection has become undetectable.

The patterns of CD8 T-cell epitopes recognized within the E6 protein in women who had cleared their human papillomavirus 16 infection were examined. T-cell lines were established using autologous dendritic cells infected with a recombinant vaccinia virus. Evidence of potential antigenic epitopes was shown in 8 of 23 (34.8%) women.

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