慢性淋巴细胞白血病患者口服氟达拉滨后的急性肿瘤溶解综合征。

The hematology journal : the official journal of the European Haematology Association Pub Date : 2004-01-01 DOI:10.1038/sj.thj.6200409

Akila Ramachandran, Gautam Majumdar

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引用次数: 6

摘要

急性肿瘤溶解综合征(TLS)是细胞毒治疗慢性淋巴细胞白血病(CLL)患者中一种非常罕见的并发症。我们报告了一位在口服氟达拉滨治疗后两次出现肿瘤溶解综合征的CLL患者。两例TLS均在治疗开始后2周以上出现。据我们所知，这是首次报道的口服氟达拉滨导致CLL发生TLS的病例。

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Acute tumour lysis syndrome after oral fludarabine in a patient with chronic lymphocytic leukaemia.

Acute tumour lysis syndrome (TLS) is a very rare complication of cytotoxic therapy in patients with chronic lymphocytic leukaemia (CLL). We report a patient with CLL who developed tumour lysis syndrome twice after oral fludarabine therapy. Both times TLS developed more than 2 weeks after the initiation of therapy. To our knowledge this is the first reported case of TLS in CLL precipitated by oral fludarabine.

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The hematology journal : the official journal of the European Haematology Association

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