人膀胱黏膜的三维结构:扫描电镜研究。

T Congiu, R Radice, M Raspanti, M Reguzzoni
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引用次数: 0

摘要

我们对人类膀胱粘膜进行了扫描电镜研究。膀胱活检标本经OsO4浸渍和1N NaOH浸渍处理后,扫描电镜观察膀胱固有层、基底层和尿路上皮的三维组织。固有层在基板下方有发育良好的毛细血管丛;尿路上皮呈典型的三层结构,有基底细胞、中间细胞和表层细胞。中间细胞的外部特征与基底细胞基本相似,从基底层向上伸展至浅层。最浅层的细胞始终呈扁平状,并通过广泛的连接复合物相互连接。它们表现出一种特殊的特化,它们的顶端质膜增厚,有独特的、坚硬的斑块,与下面的球状或纺锤形细胞相比,它们的质膜只被短的微绒毛覆盖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The 3D structure of the human urinary bladder mucosa: a scanning electron microscopy study.

We performed a scanning electron microscopy study on the human urinary bladder tunica mucosa. Specimens from bladder biopsies were treated with OsO4 maceration and 1N NaOH maceration methods prior to SEM observation to disclose the three-dimensional organization of the lamina propria, basal lamina and urothelium. The lamina propria housed a well developed capillary plexus just below the basal lamina; the urothelium presented a typical three-layered organization with basal, intermediate and superficial cells. The intermediate cells appeared essentially similar to basal cells in their external features and stretched from the basal lamina up to the superficial layer. The most superficial cells appeared consistently flattened and interconnected by extensive junctional complexes. They showed a peculiar specialization, their apical plasmalemma being thickened with distinctive, stiff plaques, in contrast with the underlying globular or spindle-shaped cells whose plasmalemma was only covered by short microvillosities.

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