Valérie Serre, Sophie Tézenas du Montcel, Linda Kontula, Monique Simon, Emmanuelle Perret, Patrick Nédellec, Patrick Vicart, Jean-Jacques Duron
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In vivo protein markers of human peritoneal mesothelial cells: do they differ according to their anatomical sites?
Objective: To highlight the in vivo protein markers in human peritoneal mesothelial cells according to their anatomical distribution and their interest in theories of peritoneal repair.
Design: Clinical laboratory study.
Setting: University Hospital, France.
Patients: Sampling of mesothelial cells during 8 laparotomies by impression smears.
Main outcome measures: Immunochemical semiquantitative measures of proteins.
Results: There were uniform ratios of protein markers among the whole peritoneal mesothelial cell population, whatever their anatomical origin (liver, stomach, omentum, small bowel, and abdominal wall).
Conclusion: This is consistent with the surrounding uninjured mesothelial cells or the exfoliated mesothelial cells, or both, having a role in postoperative peritoneal mesothelial repair.
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