氧化应激作为细胞因子释放和细胞损伤的启动器。

The European respiratory journal. Supplement Pub Date : 2003-09-01 DOI:10.1183/09031936.03.00000203a

J D Crapo

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引用次数: 90

摘要

本文介绍了氧化应激在肺病理反应中的作用以及肺所具有的独特的抗氧化防御功能。讨论了氧化还原平衡在调节炎症和免疫反应中的作用，并对哮喘和慢性阻塞性肺疾病动物模型中增强肺抗氧化能力的影响进行了表征。

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Oxidative stress as an initiator of cytokine release and cell damage.

This article characterised the role of oxidative stress in mediating pathological reactions in the lung and the unique antioxidant defences that the lung possesses. The impact of redox balance in regulating inflammatory and immune reactions were discussed, and the impact of enhancing lung antioxidant capacity in animal models of asthma and chronic obstructive pulmonary disease were characterised.

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The European respiratory journal. Supplement

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