{"title":"含Ge(IV)和Sn(IV)氯配合物的氮酮衍生物的制备及抗菌性能评价。","authors":"K I Khallow, K D Sulayman, E A al-Ubaidi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>New complexes of the general formula MCl3.L where L1 = [N-p-chlorophenyl)-alpha-(2-xanthatonaphthol)nitrone, L2 = [N-(p-anisole)-alpha-(2-xanthatonaphthol)nitrone]; M = Ge(IV) and Sn(IV) have been synthesized and characterized by elemental analyses, i.r. and molar conductances. The antibacterial activities of these ligands and their complexes have been studied against six species of bacteria in vitro at concentration ranging from 1-10 micrograms/ml. No activity were observed for the both ligands while a remarkable activities were exhibited by some complexes of both ions Ge(IV) and Sn(IV) against S. aureus, B. subtilis and P. mirabilis even more than the effect of antibacterial used in this study.</p>","PeriodicalId":9085,"journal":{"name":"Bollettino chimico farmaceutico","volume":"142 5","pages":"223-5"},"PeriodicalIF":0.0000,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Preparation and antibacterial evaluation of some nitrone derivatives with Ge(IV) and Sn(IV) chloride complexes.\",\"authors\":\"K I Khallow, K D Sulayman, E A al-Ubaidi\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>New complexes of the general formula MCl3.L where L1 = [N-p-chlorophenyl)-alpha-(2-xanthatonaphthol)nitrone, L2 = [N-(p-anisole)-alpha-(2-xanthatonaphthol)nitrone]; M = Ge(IV) and Sn(IV) have been synthesized and characterized by elemental analyses, i.r. and molar conductances. The antibacterial activities of these ligands and their complexes have been studied against six species of bacteria in vitro at concentration ranging from 1-10 micrograms/ml. No activity were observed for the both ligands while a remarkable activities were exhibited by some complexes of both ions Ge(IV) and Sn(IV) against S. aureus, B. subtilis and P. mirabilis even more than the effect of antibacterial used in this study.</p>\",\"PeriodicalId\":9085,\"journal\":{\"name\":\"Bollettino chimico farmaceutico\",\"volume\":\"142 5\",\"pages\":\"223-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2003-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bollettino chimico farmaceutico\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bollettino chimico farmaceutico","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Preparation and antibacterial evaluation of some nitrone derivatives with Ge(IV) and Sn(IV) chloride complexes.
New complexes of the general formula MCl3.L where L1 = [N-p-chlorophenyl)-alpha-(2-xanthatonaphthol)nitrone, L2 = [N-(p-anisole)-alpha-(2-xanthatonaphthol)nitrone]; M = Ge(IV) and Sn(IV) have been synthesized and characterized by elemental analyses, i.r. and molar conductances. The antibacterial activities of these ligands and their complexes have been studied against six species of bacteria in vitro at concentration ranging from 1-10 micrograms/ml. No activity were observed for the both ligands while a remarkable activities were exhibited by some complexes of both ions Ge(IV) and Sn(IV) against S. aureus, B. subtilis and P. mirabilis even more than the effect of antibacterial used in this study.