The value of urinary sediment examination as a screening method in suspected cases of metachromatic leucodystrophy.

Among the various forms of diffuse cerebral sclerosis metachromatic leucodystrophy or leucoencephalopathy has been recognised by certain clinical, biochemical and pathological characteristics [l, 2, 7, 8, 9, 101. The disease has been found to be characterized by a pathologic accumulation of sulphatides (cerebroside sulphuric acid esters). This disease occurs in an infantile, a late infantile and an adult type [5 , 6, 81; the late infantile type is the one most commonly described.