{"title":"痰液阳性的煤矿工人尘肺病与药物治疗","authors":"R.L. Sadler","doi":"10.1016/S0366-0869(58)80086-6","DOIUrl":null,"url":null,"abstract":"<div><p>Five cases with unmodified pulmonary tuberculosis in the presence of simple pneumoconiosis responded clinically and radiologically to combined drug therapy.</p><p>In contrast, little response to therapy was evident in 17 cases with positive sputa and progressive massive fibrosis. Of these cases 2 improved and 2 died, and none of the remainder showed cavity closure or a definite sputum conversion. Some cases developed drug-resistant tubercle bacilli.</p><p>The importance of classifying cases with progressive massive fibrosis by disease extent, before assessing fatality rates, is stressed.</p></div>","PeriodicalId":100202,"journal":{"name":"British Journal of Tuberculosis and Diseases of the Chest","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1958-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0366-0869(58)80086-6","citationCount":"1","resultStr":"{\"title\":\"Sputum-positive coalworker's pneumoconiosis and drug therapy\",\"authors\":\"R.L. Sadler\",\"doi\":\"10.1016/S0366-0869(58)80086-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Five cases with unmodified pulmonary tuberculosis in the presence of simple pneumoconiosis responded clinically and radiologically to combined drug therapy.</p><p>In contrast, little response to therapy was evident in 17 cases with positive sputa and progressive massive fibrosis. Of these cases 2 improved and 2 died, and none of the remainder showed cavity closure or a definite sputum conversion. Some cases developed drug-resistant tubercle bacilli.</p><p>The importance of classifying cases with progressive massive fibrosis by disease extent, before assessing fatality rates, is stressed.</p></div>\",\"PeriodicalId\":100202,\"journal\":{\"name\":\"British Journal of Tuberculosis and Diseases of the Chest\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1958-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0366-0869(58)80086-6\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Tuberculosis and Diseases of the Chest\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0366086958800866\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Tuberculosis and Diseases of the Chest","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0366086958800866","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Sputum-positive coalworker's pneumoconiosis and drug therapy
Five cases with unmodified pulmonary tuberculosis in the presence of simple pneumoconiosis responded clinically and radiologically to combined drug therapy.
In contrast, little response to therapy was evident in 17 cases with positive sputa and progressive massive fibrosis. Of these cases 2 improved and 2 died, and none of the remainder showed cavity closure or a definite sputum conversion. Some cases developed drug-resistant tubercle bacilli.
The importance of classifying cases with progressive massive fibrosis by disease extent, before assessing fatality rates, is stressed.
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