老年人主动脉瓣置换术的临床疗效分析

Bruno Chiappini, Marcello Bergonzini, Simona Gallieri, Davide Pacini, Angelo Pierangeli, Roberto Di Bartolomeo, Giuseppe Marinelli
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引用次数: 0

摘要

由于越来越多的老年患者被推荐进行手术,我们回顾了1993年至2000年间459例年龄在70至89岁之间连续行主动脉瓣置换术的临床结果。我们将研究人群细分为三组:第一组纳入70-74岁的患者;组2患者年龄75 ~ 79岁;第三组患者年龄在80岁及以上。289例(63%)患者行孤立性AVR, 168例(36.6%)患者行冠状动脉旁路移植术(CABG), 1例(0.2%)患者行孤立性室间隔缺损(VSD)闭合,1例(0.2%)患者行孤立性房间隔缺损(ASD)闭合。围手术期总死亡率为7%(32例),三组间差异无统计学意义(P=0.88)。我们的研究证实,即使是80多岁的老年患者,主动脉瓣置换术的效果也很好,仅合并冠脉搭桥手术会增加手术风险,降低长期生存率(P<0.05)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical outcome of aortic valve replacement in the elderly

Since elderly patients are being referred for surgery in increasing numbers, we reviewed the clinical outcome of 459 consecutive patients aged 70 to 89 years, who had aortic valve replacement between 1993 and 2000. We subdivided the study population into three groups: in Group 1 we included patients aged 70–74 years old; in Group 2 patients aged 75–79 years old; and in Group 3 patients aged 80 years old or older.

An isolated AVR was performed in 289 patients (63%), concomitant coronary artery bypass graft (CABG) in 168 patients (36.6%), an isolated ventricular septal defect (VSD) closure in one patient (0.2%) and an isolated atrial septal defect (ASD) closure in one patient (0.2%). The overall perioperative mortality rate was 7% (32 patients), without significant differences among the three groups (P=0.88).

Our study confirms the good outcome of aortic valve replacement in elderly patients even in octagenarians and only concomitant CABG procedures increase the operative risk, reducing long-term survival (P<0.05).

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