一种新型DNA树状大分子的合成及其性质。

Nucleic acids symposium series Pub Date : 2000-01-01 DOI:10.1093/nass/44.1.125

Y Suzuki, T Otomo, H Ozaki, H Sawai

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引用次数: 6

摘要

我们设计了一种具有刚性支链结构的新型DNA树状大分子。以1,3,5-三溴苯为原料制备了支化分子。树突状分子单元由三个寡核苷酸链，两个T15分子和一个A15分子连接到分支分子，由自动DNA合成器合成。本文将介绍树状大分子单元的性质以及由树状大分子单元的T15链和A15链的分子间缔合形成树状大分子。

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Synthesis and properties of a new type DNA dendrimer.

We have designed a new type of a DNA dendrimer which has rigid branched structure. The branching molecule was prepared from 1,3,5-tribromobenzene. The dendrimer unit, in which three oligonucleotide-chains, two molecules of T15 and one molecule of A15, linked to the branching molecule, was synthesized by an automated DNA synthesizer. The properties of the dendrimer unit and dendrimer formation by inter-molecular association of T15 and A15 chains of the dendrimer unit will be presented.

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Nucleic acids symposium series

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