毛细管电泳分离三联体重复DNA及原子力显微镜构象分析。

Nucleic acids symposium series Pub Date : 2000-01-01 DOI:10.1093/nass/44.1.67

T Nakagawa, M Ueda, Y Baba

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引用次数: 1

摘要

采用毛细管电泳和原子力显微镜(AFM)技术研究了DNA三联体重复片段的电泳行为与高阶结构之间的关系。三联体重复DNA和随机序列DNA的迁移率差异可能与其动态构象的差异有关。

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Separation of triplet repeat DNA by capillary electrophoresis and the conformational analysis by atomic force microscope.

We investigated the relationship between electrophoretic behaviors and higher order structures of triplet repeat DNA fragments by means of capillary electrophoresis and atomic force microscopy (AFM). It was suggested that the mobility difference between triplet repeat DNA and random sequence DNA should be correlated to differences in their dynamic conformation.

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Nucleic acids symposium series

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