[18F]FDG-PET对甲状腺髓样癌的诊断及应用PET/CT联合扫描的改善[18F]FDG-PET在der diagnostics de medullären children - drsenkarzinoms and die Verbesserung durch Verwendung eines PET/CT联合扫描中的应用
A. Bockisch, Katja Brandt-Mainz, R. Görges, St. Müller, J. Stattaus, G. Antoch
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Diagnosis in Medullary Thyroid Cancer with [18F]FDG-PET and Improvement Using a Combined PET/CT Scanner
[18F]FDG-PET in der Diagnostik des medullären Schilddrüsenkarzinoms und die Verbesserung durch Verwendung eines PET/CT Kombinations-Scanners
Summary: Today, positron emission tomography (PET) investigation using fluorodeoxyglucose (FDG) is the most sensitive and specific single modality established for localizing metastases of medullary thyroid cancer (MTC). Even at calcitonin serum levels below 20 pg/ml, tumour localization may be successful in individual cases. However, especially in such early tumour stages, the morphological correlation using PET is unsatisfactory. With the newly available fixed combination of PET and computed tomography (PET/CT), this drawback can be overcome as PET/CT allows a point-by-point correlation of pathological function with morphological structure. Conventional PET alone yielded an approx 80 % sensitivity and specificity in MTC: a result that will be surpassed by the combined PET/CT scanner.