[18F]FDG-PET对甲状腺髓样癌的诊断及应用PET/CT联合扫描的改善[18F]FDG-PET在der diagnostics de medullären children - drsenkarzinoms and die Verbesserung durch Verwendung eines PET/CT联合扫描中的应用

A. Bockisch, Katja Brandt-Mainz, R. Görges, St. Müller, J. Stattaus, G. Antoch
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引用次数: 41

摘要

摘要:目前,使用氟脱氧葡萄糖(FDG)进行正电子发射断层扫描(PET)是定位甲状腺髓样癌(MTC)转移灶最敏感和特异的单一模式。即使血清降钙素水平低于20 pg/ml,个别病例的肿瘤定位也可能成功。然而,特别是在这样的早期肿瘤阶段,PET的形态学相关性是不令人满意的。随着PET和计算机断层扫描(PET/CT)的固定组合的出现,这一缺陷可以被克服,因为PET/CT可以逐点地将病理功能与形态结构相关联。常规PET单独检测MTC的灵敏度和特异性约为80%,PET/CT联合扫描将超过这一结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnosis in Medullary Thyroid Cancer with [18F]FDG-PET and Improvement Using a Combined PET/CT Scanner [18F]FDG-PET in der Diagnostik des medullären Schilddrüsenkarzinoms und die Verbesserung durch Verwendung eines PET/CT Kombinations-Scanners

Summary: Today, positron emission tomography (PET) investigation using fluorodeoxyglucose (FDG) is the most sensitive and specific single modality established for localizing metastases of medullary thyroid cancer (MTC). Even at calcitonin serum levels below 20 pg/ml, tumour localization may be successful in individual cases. However, especially in such early tumour stages, the morphological correlation using PET is unsatisfactory. With the newly available fixed combination of PET and computed tomography (PET/CT), this drawback can be overcome as PET/CT allows a point-by-point correlation of pathological function with morphological structure. Conventional PET alone yielded an approx 80 % sensitivity and specificity in MTC: a result that will be surpassed by the combined PET/CT scanner.

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