职业与接触性皮炎的关系:1998年至2000年接受测试患者的评估

Robert L. Rietschel, C.G.Toby Mathias, Joseph F. Fowler Jr, Melanie Pratt, James S. Taylor, Elizabeth F. Sherertz, James G. Marks Jr, Donald V. Belsito, Frances J. Storrs, Howard I. Maibach, Anthony F. Fransway, Vincent A. DeLeo, for The North American Contact Dermatitis Group
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引用次数: 77

摘要

背景:刺激性和过敏性接触性皮炎均可受到职业性和非职业性环境暴露的影响。目的:比较职业性接触性皮炎患者与非职业性接触性皮炎患者的职业及过敏原。方法:采用美国国家职业安全与卫生研究所监测分所筛选的北美接触性皮炎组50种过敏原和职业编码进行诊断性斑贴试验。结果:在5839例接触性皮炎患者中,1097例(19%)被认为与职业相关。在职业性病例中,60%为过敏性,32%为刺激性。在64%的过敏性职业病例和80%的刺激性职业病例中,手是主要受累的身体部位。环氧树脂是唯一一种与职业接触比非职业接触更相关的过敏原。职业性病例中最常见的过敏原是碳混合料、硫脲混合料、环氧树脂、甲醛和镍。与其他职业相比,医疗领域在数据中的代表性过高。结论:职业性接触性皮炎通常是多因素的,与几种特定的过敏原和职业有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship of occupation to contact dermatitis: Evaluation in patients tested from 1998 to 2000

Background: Both irritant and allergic contact dermatitis can be influenced by occupational and nonoccupational environmental exposures. Objective: The aim of this study is to compare the occupations and allergens of occupational contact dermatitis cases with nonoccupational contact dermatitis cases. Methods: Diagnostic patch testing was conducted with the 50 screening allergens of the North American Contact Dermatitis Group and occupational coding by the Surveillance Branch of the National Institute of Occupational Safety and Health. Results: Of the 5,839 patients patch tested for contact dermatitis, 1,097 (19%) were deemed to be occupationally related. Of the occupational cases, 60% were of allergic and 32% were of irritant origin. The hands were the primary body part affected in 64% of allergic occupational cases and 80% of irritant occupational cases. Epoxy resin was the only allergen tested that was associated more with an occupational exposure than nonoccupational exposure. The allergens encountered most frequently in the occupational cases were carba mix, thiuram mix, epoxy resin, formaldehyde, and nickel. The medical field is overrepresented in the data compared with other occupations. Conclusions: Occupational contact dermatitis frequently was found to be multifactorial and associated with several specific allergens and occupations.

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