脂肪组织:心血管风险的中介。

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity Pub Date : 2002-12-01 DOI:10.1038/sj.ijo.0802210

A M Sharma

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引用次数: 146

摘要

关于与肥胖相关的心血管风险，近年来出现了两个关键发现:一个涉及到内脏肥胖作为心血管疾病风险因素的重要性，另一个涉及到脂肪组织可以被视为一个大的内分泌器官，通过分泌一些已知的调节血管、代谢、炎症和心血管系统其他功能方面的分子，直接导致心血管风险。因此，以腰围增加为特征的腹部脂肪沉积应成为肥胖个体临床干预的目标。

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Adipose tissue: a mediator of cardiovascular risk.

Two key findings regarding the cardiovascular risks associated with obesity have emerged in recent years: one relates to the importance of visceral obesity as a risk factor for cardiovascular disease, and the other to the recognition that adipose tissue can be regarded as a large endocrine organ that directly contributes to cardiovascular risk by secreting a number of molecules known to modulate vascular, metabolic, inflammatory and other functional aspects of the cardiovascular system. Therefore, abdominal fat deposition, which is characterized by increase in waist circumference, should be the target of clinical intervention in obese individuals.

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International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity

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