{"title":"棉酚和维生素E对人和大鼠淋巴细胞和精子的细胞毒作用。","authors":"M T Gonzales-garza, I Montalvo, A Sotelo","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The cytotoxicity of vitamin E, gossypol, and mixture of both was determined in lymphocytes and spermatozoa using different concentrations of the substances. The cellular viability was assessed by means of the trypan blue exclusion test at 0, 60, and 120 minutes. Spermatozoa exhibited a higher sensitivity to these compounds, which was proportional to the length of exposure and the dose.</p>","PeriodicalId":19325,"journal":{"name":"Nutrition reports international","volume":"32 3","pages":"559-64"},"PeriodicalIF":0.0000,"publicationDate":"1985-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cytotoxic effects of gossypol and vitamin E on human and rat lymphocytes and spermatozoa.\",\"authors\":\"M T Gonzales-garza, I Montalvo, A Sotelo\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The cytotoxicity of vitamin E, gossypol, and mixture of both was determined in lymphocytes and spermatozoa using different concentrations of the substances. The cellular viability was assessed by means of the trypan blue exclusion test at 0, 60, and 120 minutes. Spermatozoa exhibited a higher sensitivity to these compounds, which was proportional to the length of exposure and the dose.</p>\",\"PeriodicalId\":19325,\"journal\":{\"name\":\"Nutrition reports international\",\"volume\":\"32 3\",\"pages\":\"559-64\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1985-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nutrition reports international\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition reports international","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Cytotoxic effects of gossypol and vitamin E on human and rat lymphocytes and spermatozoa.
The cytotoxicity of vitamin E, gossypol, and mixture of both was determined in lymphocytes and spermatozoa using different concentrations of the substances. The cellular viability was assessed by means of the trypan blue exclusion test at 0, 60, and 120 minutes. Spermatozoa exhibited a higher sensitivity to these compounds, which was proportional to the length of exposure and the dose.
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