Anthony W O'Regan , Gerard J Nau , Geoffrey L Chupp , Jeffrey S Berman
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Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks
Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.
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