{"title":"α(1)-肾上腺素受体(α (1)-AR)和血管平滑肌细胞生长。","authors":"B B Hoffman, Z W Hu","doi":"10.1002/1097-0045(2000)45:9+<29::aid-pros7>3.0.co;2-z","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Smooth muscle cells in vascular tissue, like tissue within the urogenital sinus, undergo growth and proliferation.</p><p><strong>Methods: </strong>This review attempts to compare and contrast the mechanisms and controlling factors involved in prostatic and vascular tissue. There is a particular focus on the role of catecholamines and alpha-adrenoceptors (alpha-ARs), and on the effects of alpha(1)-AR antagonists (blockers) on cellular dynamics. RESULTS AND CONCLUSIONS The situation in vascular tissue appears analagous to that in prostatic tissue. Certain AR-antagonists, in addition to altering smooth muscle contraction, may have other actions on cellular dynamics.</p>","PeriodicalId":77436,"journal":{"name":"The Prostate. Supplement","volume":"9 ","pages":"29-33"},"PeriodicalIF":0.0000,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1097-0045(2000)45:9+<29::aid-pros7>3.0.co;2-z","citationCount":"8","resultStr":"{\"title\":\"Alpha(1)-adrenoceptors (alpha(1)-AR) and vascular smooth muscle cell growth.\",\"authors\":\"B B Hoffman, Z W Hu\",\"doi\":\"10.1002/1097-0045(2000)45:9+<29::aid-pros7>3.0.co;2-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Smooth muscle cells in vascular tissue, like tissue within the urogenital sinus, undergo growth and proliferation.</p><p><strong>Methods: </strong>This review attempts to compare and contrast the mechanisms and controlling factors involved in prostatic and vascular tissue. There is a particular focus on the role of catecholamines and alpha-adrenoceptors (alpha-ARs), and on the effects of alpha(1)-AR antagonists (blockers) on cellular dynamics. RESULTS AND CONCLUSIONS The situation in vascular tissue appears analagous to that in prostatic tissue. Certain AR-antagonists, in addition to altering smooth muscle contraction, may have other actions on cellular dynamics.</p>\",\"PeriodicalId\":77436,\"journal\":{\"name\":\"The Prostate. Supplement\",\"volume\":\"9 \",\"pages\":\"29-33\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2000-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1002/1097-0045(2000)45:9+<29::aid-pros7>3.0.co;2-z\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Prostate. Supplement\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/1097-0045(2000)45:9+<29::aid-pros7>3.0.co;2-z\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Prostate. Supplement","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/1097-0045(2000)45:9+<29::aid-pros7>3.0.co;2-z","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Alpha(1)-adrenoceptors (alpha(1)-AR) and vascular smooth muscle cell growth.
Background: Smooth muscle cells in vascular tissue, like tissue within the urogenital sinus, undergo growth and proliferation.
Methods: This review attempts to compare and contrast the mechanisms and controlling factors involved in prostatic and vascular tissue. There is a particular focus on the role of catecholamines and alpha-adrenoceptors (alpha-ARs), and on the effects of alpha(1)-AR antagonists (blockers) on cellular dynamics. RESULTS AND CONCLUSIONS The situation in vascular tissue appears analagous to that in prostatic tissue. Certain AR-antagonists, in addition to altering smooth muscle contraction, may have other actions on cellular dynamics.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
