{"title":"重新审视心理免疫神经内分泌综合机制。","authors":"D P Cardinali, R A Cutrera, A I Esquifino","doi":"10.1159/000014643","DOIUrl":null,"url":null,"abstract":"<p><p>This review analyzes recent publications on the topic of psycho-immune-neuroendocrine integrative mechanisms. Results on the role of cytokines in cognitive processes and in a major neuroendocrine event, i.e. the release of gonadotropin-releasing hormone, are discussed, as are the effects of cytokines on central neurotransmission. The control of immune responses by local sympathetic nerves, a major pathway in neuroimmune communication, is discussed. This review also updates information indicating that melatonin is a circulating signal affecting the periodic organization of the immune response.</p>","PeriodicalId":79565,"journal":{"name":"Biological signals and receptors","volume":"9 5","pages":"215-30"},"PeriodicalIF":0.0000,"publicationDate":"2000-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000014643","citationCount":"12","resultStr":"{\"title\":\"Psychoimmune neuroendocrine integrative mechanisms revisited.\",\"authors\":\"D P Cardinali, R A Cutrera, A I Esquifino\",\"doi\":\"10.1159/000014643\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This review analyzes recent publications on the topic of psycho-immune-neuroendocrine integrative mechanisms. Results on the role of cytokines in cognitive processes and in a major neuroendocrine event, i.e. the release of gonadotropin-releasing hormone, are discussed, as are the effects of cytokines on central neurotransmission. The control of immune responses by local sympathetic nerves, a major pathway in neuroimmune communication, is discussed. This review also updates information indicating that melatonin is a circulating signal affecting the periodic organization of the immune response.</p>\",\"PeriodicalId\":79565,\"journal\":{\"name\":\"Biological signals and receptors\",\"volume\":\"9 5\",\"pages\":\"215-30\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2000-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000014643\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biological signals and receptors\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000014643\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biological signals and receptors","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000014643","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
This review analyzes recent publications on the topic of psycho-immune-neuroendocrine integrative mechanisms. Results on the role of cytokines in cognitive processes and in a major neuroendocrine event, i.e. the release of gonadotropin-releasing hormone, are discussed, as are the effects of cytokines on central neurotransmission. The control of immune responses by local sympathetic nerves, a major pathway in neuroimmune communication, is discussed. This review also updates information indicating that melatonin is a circulating signal affecting the periodic organization of the immune response.